Aujourd'hui, près d'un actif sur deux est une femme. Ce mouvement historique de l'entrée des femmes dans le monde du travail salarié va de pair avec l'émancipation juridique et l'autonomie sociale. La difficulté de concilier vie professionnelle et vie familiale est à l'origine de nombreux bouleversements qui affectent la famille et son mode de vie.
The inflammasome is a protein complex composed of an intracellular sensor-typically a Nod-like receptor (NLR), the precursor procaspase-1, and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrates, IL-1ß and IL-18. The inflammasome has been implicated numerous diseases, and blockade of inflammasome-derived IL-1ß has beneficial effects on several of these diseases. Different books have been edited about the biology of inflammasomes and about methods to study, however, the implication of this complex in the different diseases and pathological conditions show the need of a book about the clinical implications and therapeutic options. This project will show the context where inflammasomes are being studied and the molecular implications in the medical and clinical contexts. Other important topic of the inflammasomes will be the development of pharmacological inhibitors in order to improve new clinical applications. In this sense, we can find new drugs with inhibitory effects or old drugs with an inhibitory potential effect. There is a need for re-establishing the real benefits of the inflammasome inhibitions in pathological situations and the management of the differents diseases where inflammasomes are implicated.
AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes. This book focuses on the implications of AMPK as a master metabolic regulator in diseases, including new methods and animal models. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease.
This book studies the challenges to conventional politics posed by new ways of selecting candidates for legislative elections. The recent economic crisis had profound political consequences on politics, generating an upsurge in the demand for more participative ways of decision-making in politics channelled through social movements and individuals in different countries. Some parties have reacted by introducing changes in their internal organization (via intra-party democracy), particularly related to the selection of candidates for public office. This volume explores the trends and challenges of these new methods of selection, analyses how the internet is increasingly being used as a selection tool, and evaluates some of the relevant consequences related to political representation, party cohesion and party centralization, among others.
This edited volume explores the philosophical implications of quantum mechanics. It features papers from venues of the International Ontology Congress (IOC) up to 2016. IOC is a worldwide platform for dialogue and reflection on the interactions between science and philosophy.The collection features philosophers as well as physicists, including David Albert, Harvey Brown, Jeffrey Bub, Otávio Bueno, James Cushing, Steven French, Victor Gomez-Pin, Carl Hoefer, Simon Kochen, Peter Lewis, Tim Maudlin, Peter Mittlestatedt, Roland Omnès, Juha Saatsi, Albert Solé, David Wallace, and Anton Zeilinger.
Since the early days of quantum mechanics, philosophers have studied the subject with growing technical skill and fruitfulness. Their efforts have unveiled intellectual bridges between physics and philosophy. These connections have helped fuel the contemporary debate about the scope and limits of realism and understanding in the interpretation of physical theories and scientific theories in general. The philosophical analysis of quantum mechanics is now one of the most sophisticated and productive areas in contemporary philosophy, as the papers in this collection illustrate.
This handbook covers social movement activities in Latin American countries that have had profound consequences on the political culture of the region. It examines the developments of the past twenty years, such as a renewed upswing in popular mobilization, the ending of violent conflicts and military governments, new struggles and a relatively more democratic climate. It shows that, from southern Chiapas to Argentina, social movements in the 1990s and especially in the 2000s, have reached new heights of popular participation. There is a lack of research on the politics of this region in the contemporary era of globalization, this volume partially fills the void and offers a rich resource to students, scholars and the general public in terms of understanding the politics of mass mobilization in the early twenty-first century. The contributors each address social movement activity in their own nation and together they present a multidisciplinary perspective on the topic. Each chapter uses a case study design to bring out the most prominent attributes of the particular social struggle(s), for instance the main protagonists in the campaigns, the grievances of the population and the outcomes of the struggles. This Handbook is divided into seven substantive themes, providing overall coherence to a broad range of social conflicts across countries, issues and social groups. These themes include: 1) theory of Latin American social movements; 2) neoliberalism; 3) indigenous struggles; 4) women's movements; 5) movements and the State; 6) environmental movements; and 7) transnational mobilizations.